miR-105/93-3p promotes chemoresistance and circulating miR-105/93-3p acts as a diagnostic biomarker for triple negative breast cancer

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Circulating miR-193b-3p and miR-376a-3p Involved in Iranian Patients with Multiple Sclerosis

Multiple sclerosis (MS) is an inflammatory disease that affects the central nervous system. MicroRNAs (miRNAs) are small non-coding RNAs that are usually 18-24 nucleotides long, which may have a pivotal role in the expansion of many complex diseases. The objective of this study was to evaluate the transcript levels of miR-193b-3p and miR-376a-3p in relapsing-remitting multiple sclerosis (RRMS) ...

متن کامل

Circulating miR-132-3p as a Candidate Diagnostic Biomarker for Malignant Mesothelioma

The use of circulating microRNAs as biomarkers has opened new opportunities for diagnosis of cancer because microRNAs exhibit tumor-specific expression profiles. The aim of this study was the identification of circulating microRNAs in human plasma as potential biomarkers for the diagnosis of malignant mesothelioma. For discovery, TaqMan Low Density Array Human MicroRNA Cards were used to analyz...

متن کامل

Clinical significance of circulating miR-25-3p as a novel diagnostic and prognostic biomarker in osteosarcoma

BACKGROUND Emerging evidence has suggested that circulating microRNAs (miRNAs) in body fluids have novel diagnostic and prognostic significance for patients with malignant diseases. The lack of useful biomarkers is a crucial problem of bone and soft tissue sarcomas; therefore, we investigated the circulating miRNA signature and its clinical relevance in osteosarcoma. METHODS Global miRNA prof...

متن کامل

Circulating miR-199a-3p as a novel serum biomarker for colorectal cancer.

Serum microRNAs (miRNAs) have been shown to have potential for cancer diagnosis. The main objective of the present study was to identify a novel serum miRNA biomarker from patients with colorectal cancer (CRC). Microarray analysis of miRNA expression was performed using paired pre-operative and post-operative serum from 10 CRC patients. Expression of two miRNAs (let-7a and miR-199a-3p) was sign...

متن کامل

A Prognostic Model of Triple-Negative Breast Cancer Based on miR-27b-3p and Node Status

OBJECTIVE Triple-negative breast cancer (TNBC) is an aggressive but heterogeneous subtype of breast cancer. This study aimed to identify and validate a prognostic signature for TNBC patients to improve prognostic capability and to guide individualized treatment. METHODS We retrospectively analyzed the prognostic performance of clinicopathological characteristics and miRNAs in a training set o...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Breast Cancer Research

سال: 2017

ISSN: 1465-542X

DOI: 10.1186/s13058-017-0918-2